P11S (p.Pro11Ser) variant of NOS3 (Nitric oxide synthase 3)
P11S (p.Pro11Ser) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P11S (p.Pro11Ser) variant details
- p.Pro11Ser
- ESP rs141170595
- ExAC rs141170595
- TOPMed rs141170595
- gnomAD rs141170595
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.11
- CADD 6.41
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 6.2e-05)
- Structural context available