P11R (p.Pro11Arg) variant of NOS3 (Nitric oxide synthase 3)
P11R (p.Pro11Arg) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
P11R (p.Pro11Arg) variant details
- p.Pro11Arg
- gnomAD 7-150993835-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.07
- CADD 19.60
- PolyPhen-2 0.25
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available