G27S (p.Gly27Ser) variant of NOS3 (Nitric oxide synthase 3)
G27S (p.Gly27Ser) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
G27S (p.Gly27Ser) variant details
- p.Gly27Ser
- cosmic curated COSV52489
- 1000Genomes rs372106353
- ESP rs372106353
- ExAC rs372106353
- Missense
- Variant Prioritization Score for Impact Estimate 0.0911
- REVEL 0.04
- CADD 14.10
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the 1KG:TSI population (allele frequency 0.0049)
- Structural context available