G27R (p.Gly27Arg) variant of NOS3 (Nitric oxide synthase 3)
G27R (p.Gly27Arg) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
G27R (p.Gly27Arg) variant details
- p.Gly27Arg
- gnomAD 7-150993882-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.09
- CADD 18.50
- PolyPhen-2 0.58
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available