G27D (p.Gly27Asp) variant of NOS3 (Nitric oxide synthase 3)
G27D (p.Gly27Asp) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G27D (p.Gly27Asp) variant details
- p.Gly27Asp
- ExAC rs771786669
- gnomAD rs771786669
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.04
- CADD 21.70
- PolyPhen-2 0.18
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available