G22D (p.Gly22Asp) variant of NOS3 (Nitric oxide synthase 3)
G22D (p.Gly22Asp) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
G22D (p.Gly22Asp) variant details
- p.Gly22Asp
- gnomAD 7-150993868-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.23
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available