G16S (p.Gly16Ser) variant of NOS3 (Nitric oxide synthase 3)
G16S (p.Gly16Ser) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G16S (p.Gly16Ser) variant details
- p.Gly16Ser
- cosmic curated COSV99871
- 1000Genomes rs368332097
- ESP rs368332097
- ExAC rs368332097
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.18
- CADD 22.90
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the 1KG:LWK population (allele frequency 0.0058)
- Structural context available