C15Y (p.Cys15Tyr) variant of NOS3 (Nitric oxide synthase 3)
C15Y (p.Cys15Tyr) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
C15Y (p.Cys15Tyr) variant details
- p.Cys15Tyr
- ExAC rs755834879
- TOPMed rs755834879
- gnomAD rs755834879
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.14
- CADD 23.00
- PolyPhen-2 0.81
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.7e-05)
- Structural context available