C15R (p.Cys15Arg) variant of NOS3 (Nitric oxide synthase 3)
C15R (p.Cys15Arg) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
C15R (p.Cys15Arg) variant details
- p.Cys15Arg
- ExAC rs745489730
- gnomAD rs745489730
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.20
- CADD 20.90
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available