C15F (p.Cys15Phe) variant of NOS3 (Nitric oxide synthase 3)
C15F (p.Cys15Phe) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
C15F (p.Cys15Phe) variant details
- p.Cys15Phe
- ExAC rs755834879
- TOPMed rs755834879
- gnomAD rs755834879
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.18
- CADD 23.00
- PolyPhen-2 0.74
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available