A41D (p.Ala41Asp) variant of NOS3 (Nitric oxide synthase 3)
A41D (p.Ala41Asp) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A41D (p.Ala41Asp) variant details
- p.Ala41Asp
- TOPMed rs867562196
- gnomAD rs867562196
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.09
- CADD 7.64
- PolyPhen-2 0.04
- SIFT 0.55
- Most common in the Latino/Admixed American population (allele frequency 2.5e-05)
- Structural context available