A32D (p.Ala32Asp) variant of NOS3 (Nitric oxide synthase 3)
A32D (p.Ala32Asp) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A32D (p.Ala32Asp) variant details
- p.Ala32Asp
- ExAC rs759672158
- gnomAD rs759672158
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.09
- CADD 16.10
- PolyPhen-2 0.27
- SIFT 0.11
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available