K88E (p.Lys88Glu) variant of NOS1AP (O75052)
K88E (p.Lys88Glu) in NOS1AP (O75052) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
K88E (p.Lys88Glu) variant details
- p.Lys88Glu
- TOPMed rs1655123209
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.28
- CADD 28.90
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available