R15K (p.Arg15Lys) variant of NOD2 (Q9HC29)
R15K (p.Arg15Lys) in NOD2 (Q9HC29) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R15K (p.Arg15Lys) variant details
- p.Arg15Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- MetaLR 0.13
- MetaSVM -0.97
- CADD 14.60
- SIFT 0.95
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available