H22P (p.His22Pro) variant of NOD2 (Q9HC29)
H22P (p.His22Pro) in NOD2 (Q9HC29) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
H22P (p.His22Pro) variant details
- p.His22Pro
- rs1259603692
- gnomAD 16-50697308-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- MetaLR 0.12
- MetaSVM -1.04
- CADD 7.43
- SIFT 0.39
- Population evidence available
- Structural context available
- Literature evidence available