V98M (p.Val98Met) variant of NOD1 (Q9Y239)
V98M (p.Val98Met) in NOD1 (Q9Y239) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
V98M (p.Val98Met) variant details
- p.Val98Met
- rs1422634724
- gnomAD rs1422634724
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.08
- CADD 23.20
- PolyPhen-2 0.80
- SIFT 0.03
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available