V75L (p.Val75Leu) variant of NOD1 (Q9Y239)
V75L (p.Val75Leu) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
V75L (p.Val75Leu) variant details
- p.Val75Leu
- ExAC rs762216677
- gnomAD rs762216677
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.11
- CADD 24.90
- PolyPhen-2 0.61
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available