T123S (p.Thr123Ser) variant of NOD1 (Q9Y239)
T123S (p.Thr123Ser) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T123S (p.Thr123Ser) variant details
- p.Thr123Ser
- TOPMed rs1386416465
- gnomAD rs1386416465
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.20
- CADD 24.90
- PolyPhen-2 0.90
- SIFT 0.04
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available