R35C (p.Arg35Cys) variant of NOD1 (Q9Y239)
R35C (p.Arg35Cys) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
R35C (p.Arg35Cys) variant details
- p.Arg35Cys
- ExAC rs757036750
- TOPMed rs757036750
- gnomAD rs757036750
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.25
- CADD 26.60
- PolyPhen-2 0.91
- SIFT 0.02
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available