R27W (p.Arg27Trp) variant of NOD1 (Q9Y239)
R27W (p.Arg27Trp) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
R27W (p.Arg27Trp) variant details
- p.Arg27Trp
- ExAC rs756109491
- TOPMed rs756109491
- gnomAD rs756109491
- Missense
- Variant Prioritization Score for Impact Estimate 0.603
- REVEL 0.61
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available