L145P (p.Leu145Pro) variant of NOD1 (Q9Y239)
L145P (p.Leu145Pro) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
L145P (p.Leu145Pro) variant details
- p.Leu145Pro
- 1000Genomes rs140176390
- ESP rs140176390
- ExAC rs140176390
- TOPMed rs140176390
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.36
- CADD 22.30
- PolyPhen-2 0.35
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available