L133R (p.Leu133Arg) variant of NOD1 (Q9Y239)
L133R (p.Leu133Arg) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
L133R (p.Leu133Arg) variant details
- p.Leu133Arg
- gnomAD rs1421513494
- Missense
- Variant Prioritization Score for Impact Estimate 0.677
- REVEL 0.70
- CADD 26.20
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available