H17Y (p.His17Tyr) variant of NOD1 (Q9Y239)
H17Y (p.His17Tyr) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
H17Y (p.His17Tyr) variant details
- p.His17Tyr
- TOPMed rs1264431689
- gnomAD rs1264431689
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.09
- CADD 5.27
- PolyPhen-2 0.14
- SIFT 0.73
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available