D140E (p.Asp140Glu) variant of NOD1 (Q9Y239)
D140E (p.Asp140Glu) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
D140E (p.Asp140Glu) variant details
- p.Asp140Glu
- ExAC rs779120993
- gnomAD rs779120993
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.39
- CADD 20.10
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available