C146Y (p.Cys146Tyr) variant of NOD1 (Q9Y239)
C146Y (p.Cys146Tyr) in NOD1 (Q9Y239) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
C146Y (p.Cys146Tyr) variant details
- p.Cys146Tyr
- gnomAD rs1244711059
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.34
- CADD 23.20
- PolyPhen-2 0.43
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available