Y84C (p.Tyr84Cys) variant of NLRP3 (Q96P20)
Y84C (p.Tyr84Cys) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
Y84C (p.Tyr84Cys) variant details
- p.Tyr84Cys
- rs780791430
- gnomAD 1-247419045-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.12
- CADD 24.20
- PolyPhen-2 0.78
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available