Y32C (p.Tyr32Cys) variant of NLRP3 (Q96P20)
Y32C (p.Tyr32Cys) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
Y32C (p.Tyr32Cys) variant details
- p.Tyr32Cys
- rs1452158799
- gnomAD 1-247418889-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.21
- CADD 22.90
- PolyPhen-2 0.98
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available