Y13D (p.Tyr13Asp) variant of NLRP3 (Q96P20)
Y13D (p.Tyr13Asp) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
Y13D (p.Tyr13Asp) variant details
- p.Tyr13Asp
- rs1036789973
- gnomAD 1-247418831-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.25
- CADD 24.50
- PolyPhen-2 0.75
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available