W94L (p.Trp94Leu) variant of NLRP3 (Q96P20)
W94L (p.Trp94Leu) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
W94L (p.Trp94Leu) variant details
- p.Trp94Leu
- gnomAD 1-247419075-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.30
- CADD 22.40
- PolyPhen-2 0.47
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available