W94C (p.Trp94Cys) variant of NLRP3 (Q96P20)
W94C (p.Trp94Cys) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
W94C (p.Trp94Cys) variant details
- p.Trp94Cys
- gnomAD 1-247419076-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.34
- CADD 23.50
- PolyPhen-2 0.93
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available