W68L (p.Trp68Leu) variant of NLRP3 (Q96P20)
W68L (p.Trp68Leu) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
W68L (p.Trp68Leu) variant details
- p.Trp68Leu
- gnomAD 1-247418997-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.22
- CADD 22.90
- PolyPhen-2 0.33
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available