T56M (p.Thr56Met) variant of NLRP3 (Q96P20)
T56M (p.Thr56Met) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
T56M (p.Thr56Met) variant details
- p.Thr56Met
- rs202057780
- gnomAD 1-247418961-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.17
- CADD 23.10
- PolyPhen-2 0.96
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available