R89T (p.Arg89Thr) variant of NLRP3 (Q96P20)
R89T (p.Arg89Thr) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
R89T (p.Arg89Thr) variant details
- p.Arg89Thr
- gnomAD 1-247419060-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.11
- CADD 13.50
- PolyPhen-2 0.19
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available