R89G (p.Arg89Gly) variant of NLRP3 (Q96P20)
R89G (p.Arg89Gly) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
R89G (p.Arg89Gly) variant details
- p.Arg89Gly
- gnomAD 1-247419059-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.09
- CADD 15.00
- PolyPhen-2 0.19
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available