Q35P (p.Gln35Pro) variant of NLRP3 (Q96P20)
Q35P (p.Gln35Pro) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
Q35P (p.Gln35Pro) variant details
- p.Gln35Pro
- gnomAD 1-247418898-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.06
- CADD 13.80
- PolyPhen-2 0.02
- SIFT 0.15
- Population evidence available
- Structural context available
- Literature evidence available