Q35K (p.Gln35Lys) variant of NLRP3 (Q96P20)
Q35K (p.Gln35Lys) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
Q35K (p.Gln35Lys) variant details
- p.Gln35Lys
- gnomAD 1-247418897-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.12
- CADD 4.01
- PolyPhen-2 0.00
- SIFT 0.63
- Population evidence available
- Structural context available
- Literature evidence available