P92R (p.Pro92Arg) variant of NLRP3 (Q96P20)
P92R (p.Pro92Arg) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
P92R (p.Pro92Arg) variant details
- p.Pro92Arg
- rs145774400
- gnomAD 1-247419069-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.27
- CADD 17.80
- PolyPhen-2 0.98
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available