P92L (p.Pro92Leu) variant of NLRP3 (Q96P20)
P92L (p.Pro92Leu) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
P92L (p.Pro92Leu) variant details
- p.Pro92Leu
- rs145774400
- gnomAD 1-247419069-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.05
- CADD 13.40
- PolyPhen-2 0.04
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available