P40S (p.Pro40Ser) variant of NLRP3 (Q96P20)
P40S (p.Pro40Ser) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data, published literature, and structural context.
P40S (p.Pro40Ser) variant details
- p.Pro40Ser
- rs200729212
- gnomAD 1-247418912-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0365
- REVEL 0.01
- CADD 0.16
- PolyPhen-2 0.00
- SIFT 0.53
- Population evidence available
- Structural context available
- Literature evidence available