P33S (p.Pro33Ser) variant of NLRP3 (Q96P20)
P33S (p.Pro33Ser) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
P33S (p.Pro33Ser) variant details
- p.Pro33Ser
- rs755009444
- gnomAD 1-247418891-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.07
- CADD 17.80
- PolyPhen-2 0.72
- SIFT 0.55
- Population evidence available
- Structural context available
- Literature evidence available