P33L (p.Pro33Leu) variant of NLRP3 (Q96P20)
P33L (p.Pro33Leu) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
P33L (p.Pro33Leu) variant details
- p.Pro33Leu
- gnomAD 1-247418895-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.13
- CADD 14.00
- PolyPhen-2 0.01
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available