M70T (p.Met70Thr) variant of NLRP3 (Q96P20)
M70T (p.Met70Thr) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
M70T (p.Met70Thr) variant details
- p.Met70Thr
- rs147559626
- gnomAD 1-247419003-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.28
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available