L83P (p.Leu83Pro) variant of NLRP3 (Q96P20)
L83P (p.Leu83Pro) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
L83P (p.Leu83Pro) variant details
- p.Leu83Pro
- gnomAD 1-247419042-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.723
- REVEL 0.80
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available