L83F (p.Leu83Phe) variant of NLRP3 (Q96P20)
L83F (p.Leu83Phe) in NLRP3 (Q96P20) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
L83F (p.Leu83Phe) variant details
- p.Leu83Phe
- rs775961447
- gnomAD 1-247419039-AC-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.598
- CADD 23.50
- Population evidence available
- Structural context available
- Literature evidence available