L41V (p.Leu41Val) variant of NLRP3 (Q96P20)
L41V (p.Leu41Val) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
L41V (p.Leu41Val) variant details
- p.Leu41Val
- rs868594006
- gnomAD 1-247418915-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.03
- CADD 5.38
- PolyPhen-2 0.01
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available