L41F (p.Leu41Phe) variant of NLRP3 (Q96P20)
L41F (p.Leu41Phe) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L41F (p.Leu41Phe) variant details
- p.Leu41Phe
- rs868594006
- gnomAD 1-247418915-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.13
- CADD 17.90
- PolyPhen-2 0.78
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available