L29F (p.Leu29Phe) variant of NLRP3 (Q96P20)
L29F (p.Leu29Phe) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
L29F (p.Leu29Phe) variant details
- p.Leu29Phe
- rs751660320
- gnomAD 1-247418881-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.58
- CADD 17.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available