L10P (p.Leu10Pro) variant of NLRP3 (Q96P20)
L10P (p.Leu10Pro) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
L10P (p.Leu10Pro) variant details
- p.Leu10Pro
- gnomAD 1-247418823-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.725
- REVEL 0.81
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available