K86R (p.Lys86Arg) variant of NLRP3 (Q96P20)
K86R (p.Lys86Arg) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
K86R (p.Lys86Arg) variant details
- p.Lys86Arg
- rs2103084742
- gnomAD 1-247419051-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.04
- CADD 14.10
- PolyPhen-2 0.01
- SIFT 0.72
- Population evidence available
- Structural context available
- Literature evidence available