K86N (p.Lys86Asn) variant of NLRP3 (Q96P20)
K86N (p.Lys86Asn) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
K86N (p.Lys86Asn) variant details
- p.Lys86Asn
- gnomAD 1-247419052-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.14
- CADD 19.20
- PolyPhen-2 0.72
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available